ÎČ-NAD

Common Name NAD+
Nature Naturally occurring coenzyme found in all living cells
Scientific Name Nicotinamide Adenine Dinucleotide (ÎČ-NAD)
Source found in small amounts in foods such as fish, poultry, and whole grains
Part Used Cellular coenzyme involved in metabolic reactions
  • Benefits

    • Cellular Energy Production: ÎČ-NAD plays a central role in cellular energy metabolism by supporting biochemical reactions that convert nutrients into usable cellular energy (ATP). (1)
    • DNA Repair and Maintenance: NAD+ supports enzymes involved in DNA repair processes, helping maintain genomic stability and normal cellular function. (2)
    • Healthy Aging Support: NAD+ levels naturally decline with age. Supporting NAD+ availability may help maintain cellular health and metabolic balance associated with healthy aging. (3)
    • Antioxidant and Cellular Protection: ÎČ-NAD participates in cellular defense mechanisms that help protect cells from oxidative stress and support mitochondrial function.  (1)
    • Metabolic Function: NAD+ supports normal metabolic pathways involved in carbohydrate, fat, and protein metabolism, contributing to overall metabolic health. (4)
  • ÎČ-NAD (Nicotinamide Adenine Dinucleotide)

    ÎČ-NAD, commonly known as NAD+ (Nicotinamide Adenine Dinucleotide), is an essential coenzyme present in every living cell and plays a fundamental role in cellular metabolism and energy production. It acts as an electron carrier in biochemical reactions that convert nutrients into adenosine triphosphate (ATP), the primary energy source for cellular functions. NAD+ is also required for the activity of key enzymes such as sirtuins and PARPs, which are involved in DNA repair, cellular stress responses, and metabolic regulation.

    As NAD+ levels naturally decline with age and metabolic stress, maintaining optimal NAD+ availability has become an important focus in nutritional science and healthy aging research. NAD+ precursors, including NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside), are widely studied for their potential to support cellular energy metabolism, mitochondrial function, and overall cellular resilience. (5)

Scientific Research and Studies

research and science

NAD+ and Cellular Energy Metabolism

Study Design: A biochemical and metabolic study investigated the role of NAD+ in mitochondrial energy production and cellular metabolism.

Findings: Researchers found that NAD+ functions as a critical coenzyme in redox reactions that drive ATP production, highlighting its essential role in cellular energy metabolism and mitochondrial function. (1)

NAD+ and Healthy Aging

Study Design: A clinical and molecular biology study examined how declining NAD+ levels influence aging-related cellular processes.

Findings: The study showed that reduced NAD+ levels are associated with impaired mitochondrial function and metabolic decline, while increasing NAD+ availability may help support cellular health and metabolic balance. (4)

NAD+ and DNA Repair

Study Design: Laboratory research evaluated the role of NAD+ in activating PARP enzymes involved in DNA repair.

Findings: NAD+ was shown to be essential for DNA repair pathways and maintaining genomic stability, emphasizing its importance in cellular protection and stress response. (6)

Role of NAD+ in regulating cellular and metabolic signaling pathways

Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrity

NAD+ Metabolism in Cardiac Health, Aging, and Disease

NAD+ metabolism and its roles in cellular processes during ageing

ÎČ-Nicotinamide adenine dinucleotide is an inhibitory neurotransmitter in visceral smooth muscle

Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity

  • Disclaimer: The information provided is based on scientific research and general knowledge and none of the above statements are evaluated by FDA or EFSA. This product is not intended to diagnose, treat, cure or prevent any disease.